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In vitro studies have reported that epitalon activates telomerase in human somatic cells, potentially counteracting the telomere shortening that accelerates with estrogen decline Research has explored epitalon's effects on melatonin synthesis through pineal gland modulation -- melatonin production declines with age and may further decrease during menopause, contributing to sleep and circadian disruption Animal studies have shown lifespan extension (12-13% in SHR mice) and improvements in markers associated with aging Limitations: Research is dominated by a single group (Khavinson Institute)
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The hypocholesterolemic action provided by food protein hydrolysates has been related to the release of bioactive peptides from native proteins with anti-inflammatory and anti-atherogenic activity already (Reference Gomes, Lima and Alves45)
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